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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b404d0251dc1a44805ef95f4dfb7a1094aa9e914d4c305346d29ad9c2aa43a40' 
  AND token = 'URle7axQIadl/Ytr87t7RAvoafBfPUV4p/nb7lsUzMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}