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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45fd7f5d0818c919a9a6861e24f6fea6f287f20e574a0044ab8d99946b6a93d8' 
  AND token = 'SPUrAZX0lKGUur9I+8ekylff4CiR6R2V1wXI1rwdVag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}