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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80a6e2365eb81d0d1e037fedb9412871da5bfe834dbbbcb813f4497167b21658' 
  AND token = '6wPS6Xd2/nQYzT3LTWYC6T6XncUBk9OOImbFZEaBpHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}