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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8cc6d753c2d686021409c62d3dbf9f67ce93b4952793926e5cf136ee8ab5f0c' 
  AND token = '8WLyC8d0DWkt4/r08VLlLB6utSk8tXwubY3A+bXKi0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}