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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34a2cdce9508dc4e047ceb6f2370e79018bdb3be99349b0db53698676bf22e29' 
  AND token = 'xLKHe/b+nhu0F76coEVUcxHKmcbvnZN6iWHFZGOckUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}