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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81a67d320971d414b76df02371ebd43ac92a8cdd218826b892c1f09c9af1ebbe' 
  AND token = 'x2Mg0z2Kp91aYPiIAGu3oFPm+kgaLrnDcFrCoXEwUec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}