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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb9643d1de2489dbae730f6d37235f00f173b868b4399b63b356cd6568fe01b2' 
  AND token = '27mEVzcPz6+U59LLKZVop4pUBb/EPDCmg1+hdpu60yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}