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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a143dff59716aaaf75ce68e29c627d1a393ee96e41e1484c97153c5a80ca936' 
  AND token = 'noA+Z9o4WT0xiOZT+9q6aV32J/qfqGxCrDB+qxWGp5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}