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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0de8d58689fe99d2f2cd8aeaa66eed42206483ddabb061914d35e82b0bb5121a' 
  AND token = 'BPh4XO2NubSL4tnvHgMP1ZhLPHz2d5AwwZqgVxnKLfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}