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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b07d1933162d1eb6301f36b0073cf0285eae63b52530898f5b8780b7cfefeb1' 
  AND token = 'AlpgcM2AbOrXX9STUdC5+nDLl6bl4WxBEfMInfrA0IU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}