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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3878b8183bcddd49a542eb591050d7e3c4328bffa50966fecc2e65d032a36d84' 
  AND token = 'dvMVTSJkyF96r3vnNhw3I3a/5YU6MZH5Mk8ueU7Vdic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}