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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee6a46f9c91aa86c6ab8434e60f1a239e3aa92cfa9466422e3162d258dd3da06' 
  AND token = 'gzamYywstfDYhONeVBdTFDuAPcUYS/Mw8evRHXtknfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}