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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11df4f3f9a61cc984a5c1de4c30b97bc843e7f2c6e582ee0f580bebbd159b765' 
  AND token = 'ekoXDlFV4rqjeH1IHFROiXV6owKssUk3AUVy3ftlN+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}