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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c936aef817c3cb7b0d87336213a5a2154b40a2418cf74b937ec02b9ed970445' 
  AND token = 'xSBcyboOX/UsKUB8fGbxV1zDVP7A7/rQ59IQ7P7Jiug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}