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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81a6af51b670e8644886c5e933e9a3d30fc860089f3c6ca7cfc057e2c097c655' 
  AND token = 'rjAVAkyGE6+OKaL5EgWQ6oZuTeeU74WvBFUc1I0hHCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}