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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74854123e79121b512ac23f42f764ecc6fea0dac6713cb03b21276596b2b2132' 
  AND token = '1YfNYWUJp+TNJq5SHmhj++Z4SMcATjCDh8/iWGaPaRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}