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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4190c8e6b6e8f0eed2ead5c6fefc817f77fffb1a86a3f1288c398851fe4d6abc' 
  AND token = 'acNutDJXdcffkEpPvjXERwpH57Z+6790u/OSqSO7/BE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}