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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5b58828e4e5f258fafd64e09303de05c00dda166bf5d117a3a498ebe77d5f46' 
  AND token = 'vVTXQEjR3WM+dqiz8fdErNQhAInAzzTA5lZvrjGiopw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}