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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec1561ef477ad172996f983935503fb510d3f82364af9ee5fbfd7d2b9801cd35' 
  AND token = 'XAjt07V4qCrSzi83eNklocsloPJoUE7IvcmfpfSOv1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}