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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '521c66d15bb7938e947b64ee8631e46065c64228cdefc47f52e5552868ac2fb8' 
  AND token = 'i2NJ8zvvgoHKjpE39NO5PyljTd/DV1ew7itJPV4JT2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}