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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c69602f6e78de26097ce63244337c0c1127a47b024a0304622c5b1ef702d528' 
  AND token = 'V4cFCNr/bz5BTo+lOZjbeLcOc2d9lUWSLd8SWTALME8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}