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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fdb8c350bee6b6520cde31f974f6ed5bca808ae364e35573d7812515e8fe028' 
  AND token = 'YEIz6WDBmMv9rgISmuI63SHW0E4F0OwVU+AIrfO51VM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}