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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c40e95ce980c6ed4ebcbacc5780f6b6b9666a76937dfedc2601e2c402c50cb45' 
  AND token = 'fxo1uKalBcWE45sXVqBTRu6v2gpLLNwDQAE1CRhcqDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}