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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df43a36f9f6c53ba0859c15aac496ccff5be3f2b008fcf4a896d861db16b640a' 
  AND token = '7N9sS0CitfuS5tOTB9mjwuuNSUKxPY1yzPmZodNsjRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}