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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd3b341a3f3afb38c81f3362f75057d272b40bc02e3c604e1cd06a9606604609' 
  AND token = 'ia/0GrcWH/QEc2vXRVw+FWt4Uvjeamc5q+jf8doSGv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}