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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d3e8e24de9d89e9a0e9540bd5df03541bb1d88de0f09f8aec7283142f0439e' 
  AND token = 'YOfR+pGZ0ZN+dcqZd9h7vZjqV7QNbi9bqOoGAhp2+FA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}