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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb5116d547438cd7b6f98ee1e438ff479e6612dcc1a83c5f8d64489a8a753f8' 
  AND token = 'Z8Vxh2o+R/d0LuT5vqfcC4N8SXpoKMJ/06NkAvP3JfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}