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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bc9cb210e285c4dca2f061024f248c5451078975ad9cf37e61ba24b4adec1ba' 
  AND token = '2a5oJk+PiyMnyArdPnHnZW3E16vkOu4qRGP+3nbNiiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}