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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd45475ebf47040fe12284f04938a8d6ab32da48d3a1953c2e61b84ca73cf9acb' 
  AND token = 'C/kDqI0XpP/Ri+jXKfeJPVSU4OTpqUffFImXXk84IrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}