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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b622e022cb569642baec14b62f4e2ee4ae6d5324b556135abd29f2b1db0bfffa' 
  AND token = 'MacnNJ0gi/50DtAOHk5Qx5hnCaVrcWyCWBWs9Xg1/ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}