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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4c82a4da2adf49a217096e8a08513be835000e1591e9dabaa6e6d77d2f47fd6' 
  AND token = 'YBs8XrSR7jlv210XKXzGuvH8Sdy1hx2IF9iBUF79JyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}