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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebec60c5a21bd281b45c3351c5cc5544786b01cb77a25956931e22933f1ca0d8' 
  AND token = 'nGa6X+egpkh+uiaw0m8lmH1uiCAOA/v8dEOX4nUxeWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}