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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1275a1a20042bd86c4ff0b4d13bb5130db997318b8c9f382370f159d37e58a7e' 
  AND token = '73ssDAm1x4+pR9PZY1Uv+RcmI3FoM1/Bp1KF9dox3Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}