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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37cd5cf939221fcaf326d3a2996496cfa31eecc7ed86009bc4f964f0798c436a' 
  AND token = 'QfCkN4X49K5Vh9T2NTllNAyhv+YSdt4t94o45qcqTIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}