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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '709d578a9bcd3a8550ca51ffb9ca0149a0f83f83dec1b0a207056dad87439461' 
  AND token = 'HcxSqpRIhyo+Ygi1mr3JQrrVNqJ7UySfAp/KHuO2bq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}