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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fefce48aaa5a3bd65c96551d06b9a1d871f69714ecfd0f0b20b2c725f1ebc81' 
  AND token = 'VBAorXPvLfkL36uzDcSiOYEkIcd1xC0qLlNqPc2lZsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}