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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6080b8a186256a9b8af10ad4f446a660b994d52dcf5c9eb11a762ea560dad3c' 
  AND token = 'QABWVNtDso2r5/ZuMbABcXzU8iwEFcFZNZtgGu3PlfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}