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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0edee478e45d5f71efb53b1dc19b58d111e5d9e99afbc917c28a4aad5dab24a' 
  AND token = 'JxzzRQJ4Slf1wPLcH/A/5PJ5c2Veqyympyq5V1uCgHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}