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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ccb5f9814aaeea289e0b72aeb862cda1cc5e574e394a59da4a6f34ba2807c1b' 
  AND token = 'iPjAuoEjhA0NeUKySVlhtIaM34VWah11xSWqWHlNF8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}