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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10aaa1d51aeb9db258b480fc3e05456b56ff5065cb2292b8761a334220659a3c' 
  AND token = 'IChq1oHry7yqhKJ4pURCysY3nU5EqiIILH1Nc486bY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}