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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '544b427a4d09bc05e86455788459fe95f0d779ed030f993d5a5d725ce1fd9b06' 
  AND token = 'Vqy8UqCD8yYWuMTlK51dvzOZ5QSRgdILaV+ftgWG/T8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}