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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0675e888a4f662f319fe02116405143ab0b175b135a92664b08860e0aba2aef' 
  AND token = 'rLMcB00ea5Bqyxe+B999g72C/mchXCrGh2aOb2mj04U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}