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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2513d5e1ae3ee5be8ed6042a19b8db46001062081de2ff7948e00c18ddf648f' 
  AND token = 'Cg1PyXfOxFUqM3fcatHoVPLbe5lr5YIwD+2CIyzyTRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}