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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c48c9344f8cc18ddf1e91a4a322f09d1897478ebfecfb1e7393d18a65462eb3' 
  AND token = '8+UaNK4zcS0jE/VHqecMPXXiICS7lD6B3u7QLuiQU04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}