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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '080b1c6780fa207f77c62eca7b96628dd0614c034c2d87074a5e328e4f4cd993' 
  AND token = 'nFZIt0JHzlNJu+eVY20h7SVgvmVaSWTRImd/du6zWqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}