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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09484e0d18ee3bb7a6f6e2e83a3b036036af9ada171ede8530e675b7f0da2ce8' 
  AND token = '9tDrKWc6P7P5i9F0j0+M8TT/gDBHS1eUpNYOowrWAKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}