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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12812f3882f1a0c1bc4dffc4f9a5cb965f7f39b6b7b3bead26a7597e84778f24' 
  AND token = 'zmc3eZ5lfdTfFtiMi3Z5V6MPKlHRcx4tgVaMJI+mt8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}