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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10097ec388b6b97658d581df947b865e77b1b33bc92e9dd7a69db098e925b16d' 
  AND token = 'P7yvGIwxqEt3VNTGpwdSRV10x5D5EKlj7Ss2GPS4Gp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}