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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca58b437df9df9cd19523f43a5d3857787cfa8a8886600ace4d55cd6c9caf9c' 
  AND token = 'CJDCyDIDV6OsWK/j4HULY3TMy5h3gV7xVnW+ivmWYeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}