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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae3d5b682be11ac7bf00d22b8277100d18b1c2212052193b4bb55da68b01b62e' 
  AND token = 'QqGUVnkS8IyqVZK3NDikflTRFOQ9ySc4wopolOLw084=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}